SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism.
Quercetin is a flavonoid, a class of antioxidant commonly found in fruits. Its use has been widely established particularly in Europe, for the treatment of a variety of ailments. Quercetin decreases the formation and activity of inflammation mediators in a manner that is similar to that of aspirin. An important function considering these inflammatory intracellular messengers are what cause the body's pain receptors to become more sensitive.
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