Magnesium malate is a 100% pure combination of magnesium and malic acid. Malic acid is ionized in the body to form malate, which is a key intermediate in the energy production cycle that makes ATP, the fuel that allows cells to function. Low levels of ATP are commonly found in people suffering with fibromyalgia and are believed to play a significant role in the physical and mental symptoms of the condition. A lack of ATP is also thought responsible for the muscle weakness and pain that accompanies the disease.

Studies have found that magnesium malate reduces the symptoms of fibromyalgia and chronic fatigue such as muscle pain and brain fog. Those who have been diagnosed with fibromyalgia or chronic fatigue may find some relief from its mental and physical symptoms using magnesium malate, as well as those who have not been diagnosed but have low energy levels and persistent fatigue.