B12 absorption is a complicated process. The human body cannot synthesize vitamin B12 on its own. Here are the main steps in the absorption process:
- After ingestion, B12 is separated from its food source (proteins) by hydrochloric acid which is secreted in the digestive tract.
- B12 then binds itself to a molecule in the stomach known as the “intrinsic factor”. It is this union which allows B12 to be absorbed.
- The B12/intrinsic factor complex will then travel throughout the intestine before finally being absorbed in the ileum (the end of the small intestine).
Who should take a supplement?
- Vegetarians: Vitamin B12 is mainly present in animal products. Certain vegetal sources (miso, spirulina) do contain some B12 but in a form that is only slightly absorbed by the body.
- People over age 50: 10 to 30 % of these people do not assimilate B12 due to low gastric acid levels.
- Persons affected by autoimmune diseases: self antigens will bond to the intrinsic factor rendering it unavailable for the B12.
- People suffering from chronic intestinal diseases (Crohn’s disease, Coeliac disease): this type of disease prevents the passage of vitamin B12 through the intestinal wall.
- People suffering from pernicious anemia (or Biermer anemia): these people do not secrete the intrinsic factor which is essential for B12 absorption.
Contains no dairy, wheat, gluten, yeast or corn.